Botox for TMJ

Learn about one of the TMJ treatment, Botox injections, to help relieve TMJ pain, including clenching and jaw strain.

Botox is a brand name for botulinum toxin type A, a purified protein derived from bacteria. Several other brands of botulinum toxin type A are also used in clinical practice, but at our clinic, we specifically use Botox.

Botox is FDA-approved for various medical conditions and has been extensively studied, with substantial clinical research supporting its safety and effectiveness.

Does Botox Really Help With TMJ?

Over the past several decades, there are studies to have support that Botox may help relieve pain in some patients with temporomandibular disorders (TMD) (Freund and Schwartz 2003, Von Linden 2001).

The proposed mechanisms by which Botox may reduce pain are below: 

  • Motor inhibition: reduced muscle contraction and reduced the force by causing dose-dependent muscle weakening 

  • Sensory modulation: Modulation of pain-related neurotransmitter release (SP and CGRP), potentially reducing pain signaling. (Welch et al 2000). 

  • Anti-inflammatory effects: Potential reduction of inflammation (Cui et al 2004).

Approximately 50-150 units of Botox may be used for TMD treatment with the bilateral masseter and temporalis muscles commonly targeted. However total dose, injection sites, and distribution of units are individualized based on the patient's clinical examination and treatment needs.

Full treatment effect is measured after 2 treatments (24 weeks), you may feel the results sooner.

How Risky is Botox?

Botox injections into the chewing muscles can cause side effects. Many are temporary, but their severity and duration vary. 

  • Chewing weakness or fatigue

  • Injection site reaction: bruising, swelling, tenderness or soreness

  • Headaches: headaches may occur after treatment 

  • Smile asymmetry: nearby facial muscles may be affected 

  • Change in facial contour: reduced masseter muscle volume may cause cheek hollowing or make loose skin and jowling more noticeable 

Serious complications can include difficulty swallowing, speaking, or breathing; widespread muscle weakness; and severe allergic reactions.

Seek immediate medical attention if you develop difficulty swallowing, speaking, or breathing. Call 911 for breathing difficulty or signs of a severe allergic reaction. Symptoms related to the spread of toxin effects can appear hours to weeks after treatment.

What to Know About TMJ Botox & Treatment: